Volume 18 ; Issue 1 ; in Month : 2025 (2025) Article No : 134
Amol W There* and Lalit G. Pund

Abstract

The effectiveness in scientific results is commonly obtained by adopting skilled handling and restraint techniques, which are imperative to maintain the homeostasis or adaptive state. The demonstration is designed to impart fundamental knowledge and hands-on experience in handling and restraint of laboratory animals, especially mouse and rat using descriptive and illustrative procedures. This review addresses the guidelines for handling and restraint of mouse and rat, which are usually employed in preclinical research. The cardinal objective of the review is to instill confidence in study personnel so that practicing these techniques result in reduction in stress to the animals and refine scientific outcomes. Exclusively, these techniques have been applied to the study personnel, personnel of animal house facilities, and veterinary care.

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